We describe a rare complication of this technology-calculi formation in the prostatic urethra. All patients presented with visible hematuria and variable lower urinary tract symptoms up to 5 years after the original surgery. In all cases, the calculi were successfully removed endoscopically. Possible causes for this unusual complication are discussed, and the importance of warning patients about this potential long-term complication are highlighted.”
“Preparation method was developed and a series of
ar polyconjugated compounds was obtained with (1,3-benzoxazol-2-yl)ethenyl,
(5-oxo-2-phenyl-1,3-oxazolidine)methyl moieties in the positions 3, 7 of dibenzothiophene-5,5-dione frame and with peripheral alkoxy- and alkylamine substituents in the position 1. Compounds obtained possess a strong luminescence in solutions, in the solid state, and exhibit electroluminescent properties.”
“In vivo and in vitro PR-171 cell line screening of anti inflammatory activity of Valeriana wallichii and Achyranthes aspera leaves crude extract was performed, using standardized procedures. Methanolic crude extract topical formulation (cream) of Valeriana wallichii and Achyranthes aspera leaves (Family
Valerianaceae and Amaranthaceae respectively), were screened for their anti-inflammatory activity, through “”Carrageenan induced hind paw edema”" test, for their effect on the acute and chronic phase inflammation models in male Wistar rats. Methanolic extract and its fractions were also evaluated for their in vitro anti-inflammatory activity using lipoxygenase inhibition assay. Leaves of Valeriana wallichii Selleckchem YM155 selleckchem showed significant (p<0.001), dose dependant anti inflammatory activity, comparable with that of the standard, in animal model. The ethyl acetate fraction of Valeriana wallichii also showed considerable (IC 50=73 +/- 0.36) in vitro anti-inflammatory activity as compared to standard (6.11 +/- 0.02). Similarly Achyranthes aspera leaves showed relatively weak (p>0.05) in vivo anti- inflammatory activity. However, its activity was
comparable with that of standard at 10% concentration after 5 hrs of carrageenan injection. This activity was present in ethyl acetate fraction during in vitro screening (IC 50=76 +/- 0.14) as compared to that of standard (IC 50=6.11 +/- 0.02). The combined in vitro and in vivo Antiinflammatory screening shows that the ethyl acetate fraction of the crude extract of Valeriana wallichii and Achyranthes aspera can be used for the isolation of new Anti-inflammatory lead compounds.”
“Cardiovascular disease is a leading cause of mortality among patients with diabetes, and heart failure exists even in the absence of coronary disease. Myocardial metabolism is altered in the diabetic heart as a result of changes in substrate availability secondary to insulin resistance.