We also found that activity in the Zygomaticus Major, the facial muscle responsible for smiling, was greater for reflection patterns. However, we were able to reverse this effect by changing the task so that participants had to treat random patterns as the target stimuli. We conclude that participants spontaneously select reflectional symmetry as the target, and positive affective responses automatically follow from successful target detection. This work provides a new account of the neural mechanisms involved in visual symmetry perception. (C) 2012 Elsevier Ltd. All rights reserved.”
“Objective: To examine the early
results of the David V valve-sparing aortic root replacement procedure in expanded, higher risk clinical scenarios with appropriately selleck inhibitor selected patients.
Methods: From 2005 to 2011, 150 David V valve-sparing aortic root replacements were performed within Emory Healthcare. A total of 78 patients (expanded group) had undergone the David V in expanded, difficult clinical settings such as emergent type A dissection (n = 29), grade 3+ or greater aortic insufficiency (AI) (n = 53), or reoperative cardiac surgery (n = 14). These patients were evaluated and compared with selleckchem a group of 72 patients (traditional group) with less than grade 3+AI who underwent
a David V in a traditional, elective setting. The mean follow-up was 19 months (range, 1-72), and the follow-up Amoxicillin data were 88% complete.
Results: There were 3 operative deaths (2.2%), all occurring in the expanded group. The overall patient survival at 6 years was 95%. Three patients required aortic valve replacement: two for severe AI and one for fungal endocarditis. Both groups had concomitant cusp repairs performed in conjunction with the David V (traditional, n = 10; and expanded, n = 16; P = .27). At follow-up, freedom from moderate AI was 93%, and the freedom from aortic valve replacement was 98%. No significant difference was observed in the freedom from moderate AI between the expanded and traditional groups (91% vs 95%, respectively; P = .16).
Conclusions: In selected patients
possessing appropriate aortic cusp anatomy, the David V can be safely and effectively performed for the expanded indications of aortic dissection, severe AI, and reoperative cardiac surgery with low operative risk. Valve function has remained excellent in the short term, providing evidence of durability and a low rate of valve-related complications. (J Thorac Cardiovasc Surg 2012;143:879-84)”
“Gating of sensory responses is impaired in schizophrenic patients and animal models of schizophrenia. Ketamine, an N-methyl-d-aspartate receptor antagonist, is known to induce schizophrenic-like symptoms including sensory gating deficits in humans.
This study aims to investigate the mechanisms underlying ketamine’s effect on gating of auditory evoked potentials in the hippocampus of freely moving rats.