Patients with vitamin D deficiency showed more severe disease in comparison with patients with vitamin D insufficiency, above all concerning lung involvement. Further trials are awaited to determine whether vitamin D could represent a modifiable factor able to interfere with SSc evolution.”
“The efficiency of 2,2-Dimethoxy-2-phenylacetophenone (DMPA) for the photopolymerization of methacrylate monomers in thick sections was assessed. DMPA
is an efficient photoinitiator for thick sections (approximate to 2 mm) because a fast reaction and high conversions are MAPK Inhibitor Library molecular weight obtained with concentrations as low as 0.25 wt % DMPA. The polymerization rate increased when the DMPA content increased from 0.125 wt % to 0.25 wt %. However, the conversion versus irradiation time profiles in resins containing 0.25 wt % or 0.5 wt % DMPA were similar. This is attributed to the screening effect Staurosporine caused by excessive levels of DMPA. In addition, the consumption of DMPA under UV irradiation was accompanied by the appearance
of light absorbing photoproducts. Because the absorbing species nearest to the light source absorb part of it, the light fails to reach the deeper layers of the sample. The overall effect of light screening is a reduced photoinitiation rate and double bond conversion along the irradiation path. This effect was compensated by the use of irradiation sources of higher intensity; which increased the initiation rate by increasing the production of primary radicals. DMPA is colorless and it does not require the presence of amine as coinitiator. These properties make DMPA attractive as photoinitiator of dental composites. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 123: 418-425, 2012″
“Major physiological stress occurs during cardiac surgery with cardiopulmonary bypass. This is related to hypothermia and
artificial ERK assay organ perfusion. Thus, serious gastrointestinal complications, particularly upper gastrointestinal bleeding, sometimes follow cardiac surgery. We have compared the antisecretory effects of a preanesthetic H-2 antagonist (roxatidine, cardiopulmonary bypass-H-2 group, n = 15) and a proton pump inhibitor (rabeprazole, cardiopulmonary bypass-PPI group, n = 15) in patients undergoing cardiac surgery with cardiopulmonary bypass, and also compared in patients undergoing a off-pump coronary artery bypass graft surgery (off-pump cardiopulmonary bypass-H-2 group, n = 15). Gastric pH (5.14 +/- 0.61) and gastric fluid volume (13.2 +/- 2.4 mL) at the end of surgery in off-pump cardiopulmonary bypass-H-2 groups was significantly lower and higher than those in both cardiopulmonary bypass-H-2 (6.25 +/- 0.54, 51.3 +/- 8.0 mL) and cardiopulmonary bypass-PPI (7.29 +/- 0.13, 63.5 +/- 14.8 mL) groups, respectively although those variables did not differ between groups after the induction of anesthesia.