Due to relatively higher proportion of PBDEs from octa- to deca-BDEs were detected, air inhalation and dust ingestion might be the major exposure routes of higher brominated BDEs. Further research is needed to clarify the major exposure route of
higher brominated BDEs to humans. (C) 2011 Elsevier Ltd. All rights reserved.”
“The aim of the study was to assess the changes in the quality of life (QOL) of Chinese schizophrenia find more patients and to identify their predictors over a 1-year follow-up.
A cohort of 116 schizophrenia patients was recruited, and their socio-demographic and clinical characteristics including psychotic and depressive symptoms, drug-induced side effects, social functioning, and QOL were assessed with standardized rating instruments. The patients received standard psychiatric care and were followed up for 1 year.
The psychotic and depressive symptoms, extrapyramidal side effects, and QOL domains of physical functioning, role limitations due to physical problems, social functioning, and role limitations due to emotional problems all improved significantly. Social functioning was a predictor
HDAC inhibitor drugs of baseline QOL and change at 1-year follow-up.
Routine clinical management was effective in improving schizophrenia patients’ psychopathology and several domains of QOL. QOL was related to the level of social functioning and had only a weak association with socio-demographic factors.”
“AimTo determine the efficacy of prostaglandin administration during the proliferative phase in order to improve pregnancy rates following frozen NVP-LDE225 molecular weight embryo transfer
during a hormone replacement cycle (HRC).
MethodsFrom September 2010 through March 2012, patients (n=135) were recruited who had undergone oocyte retrieval during a stimulation cycle with clomiphene and had deferred fresh embryo transfer (ET) due to a thin uterine endometrium. All patients were less than 40years of age and underwent thawed ET following all embryo cryopreservation, and were randomly divided into two groups for thawed ET using a conventional hormone replacement cycle with or without prostaglandin derivatives (prostaglandin or conventional group). Prostaglandin derivatives were administrated during the proliferative phase. Pregnancy and implantation rates following frozen ET were compared between the two groups.
ResultsAlthough the endometrial thickness on the day of ET was similar for the prostaglandin and conventional groups, the pregnancy and implantation rates for the prostaglandin group were 40.0% and 22.0%, respectively, which was significantly higher than the rates for the conventional group (P<0.01).
ConclusionAmong patients who avoided fresh ET due to a thin endometrium, the pregnancy rate following a thawed cycle was low.