A diagnosis of EOPPC was made after a thorough study.
A correct diagnosis and timely management of this unusual histologic
entity can result in long-term disease-free survival of the patient.”
“We present a theoretical study on the impact of a waveguiding active layer on the emission properties of an ultrathin luminescent film. While the study can be generalized to any material, we focus here on a simple layered medium composed of a conjugated polymers (CPs) thin film, a zinc oxide layer (ZnO) and a sapphire substrate. The study spreads throughout variable aspects including the effect of the structure parameters on the CP luminescence and radiation pattern and more specifically the selleck compound influence of the absorption and emission properties of the active layer. Comparing between the passive and active layer cases, the obtained results show that an enhancement of the CP luminescence of more than 20 times can be obtained by using an optically active waveguiding underlying layer. The results can be explained in terms of photon recycling where the optically active layer acts as a photon reservoir and a secondary light source for the
ultrathin film. This general concept is of a special interest for ultratrace chemosensor. (c) 2010 American Institute of Physics. [doi: 10.1063/1.3524537]“
“BACKGROUND: Patients with congenital heart disease (CHD) now survive into adulthood and often present with end-stage heart failure (HF). HE management and approach to orthotopic heart transplant (OHT) may differ from adults without CHD. We sought to compare OHT waitlist BLZ945 characteristics and outcomes for these 2 groups.
METHODS: The Organ Procurement and Transplantation Network (OPTN)/United PHA-739358 Network for Organ Sharing (UNOS) database was used to identify adults (18
years) listed for OHT from 2005 to 2009. The cohort was divided into those with or without CHD.
RESULTS: Of 9,722 adults included, 314 (3%) had CHD. Adults with CHD were younger (35 +/- 13 vs 52 +/- 12 years, p < 0.01) and more often had undergone prior cardiac surgery (85% vs. 34%, p < 0.01). Patients with CHD were less likely, to have a defibrillator (44% vs 75%,p <0.01) or ventricular assist device (5% vs 14%, p <0.01) and were more likely to be listed at the lowest urgency status than patients without CHD (64% vs 44%, p <0.01). Fewer CHD patients achieved OHT (53% vs 65%, p < 0.001). Although overall waitlist mortality did not differ between groups (10% vs 8%, p = 0.15),. patients with CHD were more likely to experience cardiovascular death (60% vs 40%, p = 0.03), including sudden in 44% and due to HF in 16%.
CONCLUSIONS: Despite lower urgency status, patients with CHD have greater cardiovascular mortality awaiting OHT than those without. Increased defibrillator use could improve survival to OHT, because sudden death is common. VAD support may benefit select patients, but experience in CHD is limited.