2) 118.4 (3.9) Sex (%) Male 7,121 (100.0) 49.6 Female 50.4 Height (cm) 7,047 (99.0) 139.5 (6.3) Weight (kg) 7,105 (99.8) 33.2 (29.4–38.4)a TBLH
BMC (g) 6,775 (95.1) 893.8 (184.0) TBLH BA (cm2) 6,775 (95.1) 1139.5 (164.3) TBLH BMD (g/cm2) 6,775 (95.1) 0.78 (0.05) TBLH ABMC 6,775 (95.1) 894.6 (39.8) Spine BMC (g) 5,487 (77.1) 78.4 (15.7) Spine BA (cm2) 5,487 (77.1) 100.7 (12.0) Spine BMD (g/cm2) 5,487 (77.1) 0.77 (0.08) Spine ABMC (g) 5,487 (77.1) 78.4 (7.1) Pubertal stage (%) Boys Tanner 1 2,365 (67.0) check details 82.9 Tanner 2 16.5 Tanner 3+ 0.6 Girls Tanner 1 2,836 (79.0) 81.5 Tanner 2 15.0 Tanner 3+ 3.5 Age at menarche for girls (years) (%) Up to 10 3,107 (86.5) 4.7 11+ 95.3 Gestational age (weeks) 7,121 (100.0) 39.5 (1.8) Birth weight (kg) 7,035 (98.8) 3.4 (0.5) Household social class (%) I 6,544 (91.9) 15.5 II 45.1 III NM 24.8 III M 10.3 IV/V 4.3 Mother Age at delivery (years) 7121 (100.0) 29.0 (4.6) Height (cm) 6753 (94.8) 164.1 (6.6) Pre-pregnancy BMI (kg/m2) 6429 (90.3) 22.2 (20.5–24.4)a No. of previous births (%) 0 6879 (96.6) 45.8 1 35.5 2 13.7 3 3.8 4 or more 1.2 Smoking during pregnancy (%) Never 6379 (89.6) 78.7 1 or 2 trimesters 9.5 All trimesters 11.8 Education (%) None/CSE 6860 (96.3) 13.8 Vocational 8.5 O Levels 35.2 A Levels 26.6 Degree 15.8 Father STA-9090 Age at child’s
birth (years) 5106 (71.7) 31.4 (5.2) Height (cm) 4931 (69.2) 176.3 (6.9) BMI (kg/m2) 4887 (68.6) 24.8 (22.9–26.9)a Regular smoker (%) No 6679 (93.8) 65.3 Yes 34.7 Education (%) None/CSE 6467 (90.8) 19.3
Vocational 8.2 O Levels 21.7 A Levels 28.5 Degree 22.2 ABMC area-adjusted bone mineral content, BA bone area, BMC bone mineral content, BMD bone mineral density, BMI body mass index, IQR interquartile Farnesyltransferase range, TBLH total body less head aMedian and interquartile range are shown for skewed variables Pairwise correlations of total body and spinal bone measures are given in ESM Web Table 3, and correlations of these measures with child and parental characteristics are shown in ESM Web Table 4. The child’s height and weight were strongly positively correlated with TBLH and spine BMC and BA and moderately with TBLH and spine BMD. Higher birth weight, longer gestation and greater age at DXA scan were all associated with increased TBLH BMC, BA and BMD. Multiple imputation analysis of maternal and paternal smoking in relation to TBLH bone outcomes is shown in Table 2 and the analysis of spinal outcomes shown in Table 3.