An Egy-Score of 3.67 or more was superior to APRI, FIB-4 and Forns’ index for detecting cirrhosis with a sensitivity of 82% and specificity of 87%. Forns’ index was superior to Egy-Score, FIB-4 and APRI for detecting significant fibrosis. The Egy-Score is a promising, accurate, easily calculated, cost-effective score in the prediction of hepatic

fibrosis in chronic HCV patients with superiority over APRI, FIB-4 and Forns’ index in advanced hepatic fibrosis and cirrhosis. “
“Background and Aim:  To estimate the sero-prevalence of Helicobacter Pylori infection in the Australian adult population and identify determinants. Methods:  We analyzed serum samples and questionnaire data Silmitasertib mw from 1355 community controls who participated in a nationwide case-control study of esophageal cancer in Australia between 2002 and 2005. We estimated the prevalence ratio and 95% confidence interval using log binomial regression models. Results:  The age and sex standardized sero-prevalence of H. pylori was 15.5%. The prevalence of infection varied significantly with age, ranging from 5% selleck products (< 40 years) to 32% (≥ 70 years). H. pylori infection was significantly higher among those born overseas (prevalence ratio [PR] 1.63; 95% confidence interval [CI] 1.34–1.98) compared with those born in Australia or New Zealand. H. pylori sero-prevalence

was 23% higher among participants living in the lowest quartile of socio-economic areas (PR 0.77; 95%CI 0.59–0.99 for Q4 compared with Q1). H pylori serostatus was

significantly inversely associated with university education (PR 0.56; 95%CI 0.38–0.83), frequent reflux symptoms (PR 0.62; 95%CI 0.42–0.91), use of proton pump inhibitor (PR 0.69; 95%CI 0.48–0.98) and use of medications for gut spasms (PR 0.48; 95%CI 0.25–0.93). H. pylori serostatus was not associated Phosphatidylinositol diacylglycerol-lyase with body mass index, smoking, alcohol or physical activity. Conclusions:  The prevalence of H. pylori infection in Australian adults is lower than other developed countries. H. pylori infection is most common among those living in the areas of socio-economic disadvantage or who were born overseas. “
“AASLD/ASGE Endoscopy Course Friday, November 1 7:55 AM – 3:00 PM Room 146A Endoscopy in Patients with Hepatobiliary Disorders: Evolving Concepts, Technologies and Techniques COURSE DIRECTORS: Subhas Banerjee, MD Barham K. Abu Dayyeh, MD 6.5 CME Credits The overall goal of this activity is to educate the target audience in state-of-the-art best practices pertaining to diagnostic and therapeutic endoscopy in patients with hepatobiliary disease. This should result in a significant improvement in their understanding of the relative benefits and risks of these modalities, in optimizing patient selection for different endoscopic interventions and in the performance of these endoscopic interventions.